safety and efficacy of the 1540nm non-ablative fractional XD probe of star lux 500 device in the treatment of Striae alba: before-after study

Striae distensae [SD] are a frequent skin condition for which treatment remains a challenge. The 1540-nm non-ablative fractional laser [Star Lux 500] has been shown to improve atrophic scars by increasing the amount of dermal collagen. To assess the safety and efficacy of the Star Lux 500 laser in the treatment of mature hypopigmented striae in Persian people [Striae Alba]. Ten women aged 26-50 years with SD and Fitzpatrick skin types III-V were enrolled in the study. The exclusion criteria were a history of keloids, photosensitivity and collagen, elastin disorders as well as history of other striae treatment within one year. The lesions were treated with non-ablative fractional laser 1540nm, and a total of four treatments were given at 4-week intervals. Clinical standard photographs were taken before each treatment. Also, patients were followed up at 3 months after the last treatment. Clinical improvement was assessed by comparing baseline and post-treatment photographs by two independent blinded physicians using grading scale. Treatment efficacy analysis was performed via the comparison between the images taken before and after each treatment session. There was a clinically appreciable improvement in striae ranging from 1 to 24%. A significant improvement in striae between the 16-week treatment and the 4-week treatment was identified [P<0.0001]. Three months after the final treatment, patients showed noticeable improvement in the striae, compared with baseline [P<0.048]. Mild post inflammatory hyperpigmentation was observed in one patient after the 8-week treatment and mild to moderate acne occurred in another patient after 4 weeks of treatment. Therapy with Star lux 500 laser had clinically and statistically striae improvement with no adverse events. This may be a safe and an effective treatment modality for Striae Alba lesions

Ablative fractional co[2] laser may be a novel treatment for tattoo allergic reaction

A 47 year-old woman presented with eight-month history of tattoo allergic reaction of eyebrows after botulinum toxin A injection that was resistant to oral, topical and intralesional injection of corticosteroids. Multiple sessions of treatment with CO2 fractional laser resulted in significant flattening of allergic papules and plaques as well as reduction of tattoo pigmentation.

Evaluation of efficacy of intense pulsed light [IPL] system in the treatment of facial acne vulgaris: comparision of different pulse durations; a pilot study

Adequate control of acne is difficult, regardless of the various conventional modalities. Intense Pulsed Light [IPL] system is one of the emerging options that are become increasingly useful. To achieve the best IPL parameters we evaluated the efficacy and tolerability of IPL at 752-nm wavelength, 35 j/cm2 fluence, 55-ms pulse duration in comparison with 572-nm wavelength, 35 j/cm2 fluence, 101-ms pulse duration, in a 5 week, controlled, double-blind, split-face clinical trial. Final assessment was made by comparison of the changes in inflammatory and non-inflammatory acne lesions count and the Acne Global Severity Scale [AGSS] between two groups, based on standardized photography. Fifteen female patients, with mean age of 23.53 +/- 2.47 years [range 20-28] completed the 5-week therapy period. For both therapies, significant reductions [approximately 30%] in the comedone and inflammatory lesions count were observed [p=0.0024]. There was no significant difference in the efficacy of the two treatments in reducing the percentage of comedone and inflammatory lesions count from baseline to 5th week [p=0.76 and p=0.61, respectively]. Based on acne global severity scale [AGSS], no significant difference in the severity of acne lesions of the two treatments was observed at 5th-week visit [p=0.26]. Considering the lack of significant difference between the two treatments and since greater risks are associated with lower pulse duration, the use of longer pulse durations is recommended, especially in darker skin phenotype. Further studies with larger number of patients are required to fully comparison of efficacy of these parameters in IPL systems for acne vulgaris

use of intense pulsed light [IPL] for the treatment of vascular lesions

According to the English literature, various lasers and light sources [i,g. argon ion lasers, pulsed KTP lasers, diode lasers and Nd: YAG lasers, pulsed dye laser [PDL], intense pulsed light sources [IPLS] are applicable for the treatment of different vascular lesions. These conditions are the most important indication for laser therapy. This review summarizes the current literature on IPL with regard to the treatment of vascular lesions